Where are the cool alien planets? The spaceships? The ladies (of legal age)?
With transwarp and quantum slip stream technology, further reaches of space can be explored, they can center episodes like that around tag-alongs with other vessels or maybe a new scout class vessel used for college use or class away missions. As for ladies, you won't just have college girls but maybe a sexy teacher, nurse, or milf ('Mother Inclined to Largen the Fleet' of course).