I think after Enterprise no TV series would have revitalized the series.
Maybe after DS9 and Voyager a different series could have done it. Actually if Enterprise season 1 were more like season 4, it might have helped save the franchise.
But the series I would have liked to see produced was one that continued into the future, where after the Dominion War the Federation started reconsidering the policy of exploration and diplomacy, and people started giving away civil liberties, that focused on a group of former Starfleet officers who left the Federation because they believed in its original values.
Something like that would have been perfect for 2001.