Ship: U.S.S. Prometheus
First Officer: Sisko if that's allowed, otherwise Spock
Second Officer: Kira
Tactical/Counselor: Worf (Don't tell me Counselor Worf wouldn't be awesome.)
First Assistant Engineer: Barcalay
Medical: The Doctor
Morale officer: Quark
Captain Picard and first officer Sisko? Gee they might not get along so well.