Some of you guys need to get a grip dammit!
STID will cross the $300 million dollar mark this weekend (global total) and by the end of its run, will probably make $400-$500 million. This will make it the most successful Trek movie ever (bar the possible exception of TMP).
Crikey - it's going to beat Star Trek 09's global gross and do rather nicely, thank you very much.
I've used a few inflation calculators, and TMP's 1979 worldwide take of $139,000,000 is worth roughly $433,000,000 in today's money. I realise there are many other factors to take into account, but I do think the comparison is a fair guide.
Based on that, STID has a good shot at becoming the most successful Trek movie - when judged by the final dollar tally at least.