A is for Admiral Archer's prized beagle, Athos. Descendant of Porthos. His wherabouts and condition are unknown.
B is for Beta Niobe, the star that went supernova and destroyed the planet Sarpeidon
C is for Classified. The Corbomite device is.
D is for Deneva, home of Sam and Aurelan Kirk.
E is for Excelsior. She's supposed to have trans-warp drive.
F is for Fesarius, Balok's ship in "The Corbomite Maneuver"
G is for Glommer. Tribble predator.
H is for Herm Gossett, lithium miner who marries one of "Mudd's Women"
I is for Isolinear optical processors, standard Federation computer technology aboard Starfleet vessels beginning around 2329.
J is for Janice Lester, Kirk's craziest ex-girlfriend
K is for Kaferian apples.
L is for Loskene, Tholian starship commander
M is for Mars Defense Perimeter, obliterated by the Borg cube following the massacre of Starfleet at Wolf 359.
N is for Nilz Baris, annoying Federation bureaucrat
O is for the Orb of Time, which was once indirectly connected to the entry for N.
P is for Protomatter. A dangerously unstable form of matter.
Q is for Quark's fashion sense. For a Ferengi he was a pretty snazzy dresser.
R is for Romulan Rage: SPOOOOOOCK!!!
S is for Sehlat. It's like a Vulcan teddy bear, only they're alive and have six-inch fangs.
T is for T'Pol's derriere.
U is for United Earth Alliance, the formal name for the interplanetary forces aligned against the Romulans during their war of 2156-60.
V is for Valeris' treachery.
W is for Wesley Crusher going "Wow!"