I've been thrilled by Aku no Hana, or Flowers of Evil lately. Crazy loner girl bullies emo teen boy who takes quivering to amazing levels. It's drawn over live actors, looks naturalistic, but more over-dramatically emotive than any cartoon or live action character, so every single movement is utter hilarity, while rawly tragic
You know you want to watch it...
7 out of 13 episodes have aired. First one is funny because of how ludicrously portentous it can be, even though nothing happens. After that every episode is better, and more eventful than the last.