Larry Nemecek as Bones. He wasn't bad, I liked the expressiveness of his acting, but I liked Chuck Huber better in the vignettes. I think part of the problem is that he seemed a bit too much like Dr. Piper from the first pilot than McCoy...
I watched this late last night at 3 am. I have to admit that when I first saw the doctor appear on screen, my first thought was "Dr. Piper is in this?"
I think he looks and sounds more like Piper than he does Bones. All in all, I thought this was a great first episode. They did a really great job, and there was a lot of easter eggs in the episode for fans to enjoy. The introduction of the holodeck was also inspired. All of the acting was top notch. Chris Doohan as Scotty was beyond amazing!