What makes it different from something like Alphas or Fringe is that they're not afraid to use the word "superhero." It will be nice if this show draws as heavily on Marvel lore as Arrow or later-seasons Smallville have drawn on DC lore. Hopefully we'll get some significant supervillains too.
Well for me it's not enough to simply use the term-- I want to see characters that actually LOOK like superheroes and supervillains on this show, who have a whole, comic book style mythology and look like they could almost stand alongside Cap and Thor in their outfits.
If it's just a bunch of troubled loners in normal clothes who have weird powers and abilities, then that's something I feel like I've already seen to death by now.