Re: Joss Whedon's S.H.I.E.L.D to ABC!
^ That's the part that is exciting. Even though this will be self-contained from the MCU...there is still a whole entire rest of the Marvel Universe they can explore and use if they so wish. Start developing lesser known characters, etc. Maybe even incorporate elements like "AKA Jessica Jones" or even their proposed "Cloak and Dagger" series. This just opens up the Marvel Universe a bit more. I'm really excited for this.
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Ignoring the The Last Stand since 2011.