Soran, Borg Queen, Ru'afo and Shinzon, have been nothing more than stupid attempts to make a Khan like villian, just give us Khan for god's sakes.
Ru'afo and Shinzon, yeah, I can make that connection. Soran and the Borg Queen though, I don't see it. Neither were on any kind of quest for vengeance.
Sorin was trying to gain immortality and escape the pain of the loss of his family. The key difference is that Khan was trying to avenge
the loss of his family. Sorin merely wanted to forget, which is a fairly significant distinction. He wouldn't have killed anyone if there had been another way to enter the Nexus.
And the Borg Queen's motivation was the same as what the Borg's motivation has always been: assimilation and conquest.