Well, I only mean 'bias' in the sense of the basic assumptions that everyone begins with, that are just a function of the culture you were raised in and the personality you have. Nobody is neutral, we all have our own history and culture that we perceive the world through.
For that matter, I said 'in the real world' above. Looking at it closer, all of the above still applies to the 'real world' just as much as it does to DS9. There are a lot of similarities between the belief in a god and the belief in aliens. They're both external expressions of the same innate part of human nature - the need to believe that there is something larger than us, something else out there, that this is not all there is. It's just the same science-religion dichotomy I was talking about earlier in the thread. You might fall on one side of the line or the other, but it doesn't really matter in the long run because they're just different ways humans have found to deal with the same subjects.
In the podcast, Chris referred to the "ancient astronaut" theory - that what people perceived as gods at the time were actually visitations by alien lifeforms. Is that really so hard to believe? It's only the same as the aphorism that any sufficiently advanced technology will appear to be magic to those who don't understand it.
Look at Christ rising up into heaven. How is that different from people's accounts of alien abduction? Look at Zeus descending from Mount Olympus of a chariot of flame. How is that different from an alien spaceship coming in to land?
And look at the examples in Star Trek
itself, aside from the Prophets. Christians believe God made man in his own image. How is that different from the progenitor aliens in "The Chase" ? They believe God is looking over us, guiding us, leading us on the right path, stopping us from doing bad things. How is that different from the Vulcans of Enterprise
Again, my point is that there's no need to choose. It's not an either/or thing. They're both basically the same.