A is for Assassination. Klingon Chancellor Gorkon was the victim of one in early 2293.
B is for Beta Quadrant. Location of various gaseous anomalies.
C is for California, the location of Starfleet Headquarters, Starfleet Academy and the San Francisco Ship Yards.
D is for Devil. Klingons don't have one but they know the habits of ours.
E is for Enterprise CVN-65, the nuclear-powered American aircraft carrier that bore the famous name during the late 20th and early 21st centuries.