Game Of Thrones is as far from "lostesque" as it can possibly be.
I did watch Invasion, FlashForward and Event though. Invasion was pretty cool, the rest were just silly ... Now, I don't watch those shows anymore. Shows that are made by inventing stuff on the spot are not my thing anymore.
The characters on LOST were good (well, most of them), but when the entire show is built on mystery upon mystery until the mysteries overshadowed everything else, you kind of expect those mysteries to be answered. When the show ended with "fuck the mysteries, it was about characters all along" explanation and with that stupid cave plug bullshit, I understood that I wasted time on something that was never intended to be resolved or was ever supposed to make sense.