A is for Alpha Centauri, one of the very first star systems outside of Earth's that was colonized by human beings.
B is for the Beta Renner system. Whose two species, the Anticans and the Seley. Apparently have developed a taste for each other. And not in a good way.
C is for Charlie Evans.
D is for a Day. The Genesis matrix took only this long to form.
E is for the Edo. A good choice for a franchise location for Risa.
F is for Farragut. The Constitution-class one. James T. Kirk's very first assignment after graduating from Starfleet Academy in 2254.
G is for Garrovick, the Farragut's captain.
H is for Harry Mudd's entertaining moustache.
I is for I Am Not Spock.