Sure, Picard experiment some while he was at the Academy, who didn't?
That how he first became "friends" with Jack Crusher. But Jack, even after his marriage to Beverly, wouldn't let go, and it was necessary for Picard to send Jack on a away team mission where he would surely be killed.
Picard felt guilty about that decision for years. It was only in the arms of the transvestite Vash that he could find solace and relief.