I don't remember the name of the episode, but what about the episode where O'Brien is tried in Cardassian court? That is extremely interesting and specific.
DS9 does have it's share of skippable episodes, but compared to Voyager or seasons 1-2-7 of TNG, not so much. It's true some of the Ferengi episodes are awful, but a few of them work.
The worst thing to happen to the Ferengi was Moogie.