I think the guardians of NuTrek should (at the very least) consider moving away from the 22 episode/starship/alien of the week formula.
I'd like to see something a bit different:
1. Why not reduce the number of episodes per series? If a Trek spin-off consisted of, say, six ninety-minute episodes, the visual/conceptual scope of the series could be greatly enhanced. In the UK, the BBC's flagship programmes usually follow this format (i.e. Sherlock).
2. What about jettisoning the starship? Follow the exploits of a group of cadets at the Academy, a team of undercover anthropologists on a strange new world, or a federation diplomat caught in a morally ambiguous bind.