The initial problems I had with Enterprise in first run was adjusting to some of characterizations and story elements (like "Acquisition"). I started missing episodes late in the 2nd or early 3rd season, so I never understood what was going on in the Xindi arc, and when I would catch an episode it was usually one of the lackluster stand-alones. I didn't see the 4th season at all until this year.
Some of the problems were because for a while, my landlord forced a situation where I was sharing a unit with a manic-depressive (who was legally insane) who not only ripped my (purchased) telephone out of the wall but eventually leaped through the closed living room window while trying to elude police. Thank God I never saw him again.