The Other Guys has some of my favourite of dialogue in the series.
Dr. Felger: "At least my heroes actually exist. If we were home you'd be at a Star Trek convention dressed like a Klingon."
Dr. Coombs: "Vulcan! And how can anyone call themselves a scientist without worshipping at the altar of Roddenberry?"
Dr Felger: "'How do we solve this one, Captain?' 'I don't know, something to do with the tachyon emitters, perhaps?'"
Dr. Coombs: "Oh, we might as well be wearing red shirts."
Dr. Felger: "You know, I don't get that."