Dale Sams wrote:
Was Barrymore filmed at all before he was replaced on The Alternative Factor? Then there's Genvieve Bujold. Neither was a death, but similar circumstances.
Max already answered about Barrymore; Bujold's footage can be seen as an extra on the Season 1 Voyager DVD. I never bought it, but I borrowed it from a coworker just to see her.
She's a very good actress, but she did seem out of place in a leadership role. Mulgrew was a better choice.