Sisko went through pain, grief, and anger for three years following Wolf 359 and finally encountered the man whose face was forever etched in his mind as the one responsible for it all. Sure, you can say his anger was misplaced, but when he saw Picard, he didn't see a fellow Starfleet officer, but rather Locutus of Borg. Sisko had to undergo a personal journey (albeit with the help of the Wormhole aliens) to let all of that go and start living again.
So in "Emissary," a still grieving Sisko felt some initial resentment towards Picard--but he got over it by the end of the episode
. Hating Sisko because he wasn't from the start a card-carrying member of the Picard Fan Club is lame.