Since it's Original Series and therefore the most well-known, iconic characters who are destined to be recast forever now it seems, yadda-yadda... CBS could try getting a reanimation project underway. It'd sell to a network someplace, simply because it's the further adventures of Kirk, Spock and McCoy. No money to lay out on script writers, voicing talent or musical direction. Care would be needed to match new animation with the already set soundtracks. I gather that's the opposite way round to how cartoons are generally made... with the possible exception of Doctor Who's interest in producing visuals to accompany the soundtracks to lost episodes.
Split the 22 episode run in half, for a equal length two season run, with the Blu ray featuring the original Filmation cartoons on one angle and the new style on the other. Go the seamless branching route remastered TOS did.