By the time of Nemesis
, Picard and Riker had essentially flipped roles with the former leading away teams and the latter staying behind on the bridge. A TNG reboot could merely start from that position.
Picard could be a seasoned, no-nonsense war veteran that was contemplating retirement when Starfleet offers him command of its newest dreadnought, the Enterprise
. Picard soon finds himself having to break in a battle-inexperienced crew, including a cocky young first officer and an android second officer.