Re: If the Doctor was female
It would be kind of fun if they did do a story where the Doctor's Tardis somehow wound up in a reality where well... he was a she and his/her choice in companions changed or maybe stayed the same, but it was a different dynamic. While I don't particularily see a lesbian Doctor, I could see him having a motherly/sisterly relationship with some of his companions.
If anything the most 'Butch' would be 9 - not really wanting to be a mother figure or sister. 10 I could see being a bit more sisterly/best friend with Rose. 11 she'd just be quirky and awkward and geeky and maybe a little more friendly rivalry with Amy. River Song would probably still be her 'wife' - she looks like she could swing either way LOL
"Here you are in the club with your bottle full of Bud, you got grillz you got bling, but playa you don't know a thing..." Alice Cooper - Disco Bloodbath Boogie Fever