When Dax and Sisko exit the wormhole on the GQ for the very first time, the computer identifies the Idran System as less than 5 ly away. Basis of the identification is an 22nd century analysis of the 'Quadros-1 probe of the gamma quadrant'.
Of course, we don't know if that means Quadros-1 actually was in
the gamma quadrant. If it is, we'd probably have to subtract at least another 70 years from that time, as I think it would be unlikely 24th century starships could still not fly as fast as a 21st/22nd century probe. So I would tend to think this was actually a long-distance analysis. But still... the 'Friendship' ep from VOY doesn't rule it out imho.