The part of the interview that most interested me was the talk of mining the X-Men universe. I had been hoping for something like this.
I would be cool to keep the First Class timeline going, showing early exploits. Then you could have a present day timeline with the original cast, or even solo films like Wolverine. Doing a spin-off like X-Factor or even Excalibur set in the present timeline would also be cool. You could bring back an older version of Havok for X-Factor and get Nightcrawler back for Excalibur.
If done right, as Marvel has to date, they could do some amazing stories and have cool cross-overs. Maybe like introducing Apocalypse in X-Factor in a small role, and then having him be a huge villain in an X5 or something.