Yes, but that's where you use missiles instead of fighters.
Missiles are single use drones.
Multiple use drones have many advantages over single use missiles in a space battle.
Over very large distances - as in space -, in order to be effective, both missiles and drones need capable AI (eliminating humans from the command chain - which presents disadvantages) or remote control (which can be jammed).
Manned fighters don't have this problems - but have others, which can be summed up as higher mass.
A heavily shielded/cloaked station, housing the humans, and multiple drones operating at close range (minimizing the AI and jamming problems) could be the best solution.