I did, up until a year and a half ago, when I moved away from the group. Tried quite a few games, D&D 3.5, Mutants and Masterminds, various WOD games.
We had two short lived sci-fi games. The first was in d20 Modern with the Future expansion. Problem is that expansion was pretty broken. The second game we tried GURPs 4th edition, but none of us liked that either. There was talk of starting a third game in True 20, but it never got off the ground.