If one takes out the space and sci-fi stuff out of Andromeda, the show would probably resemble a generic western or a mediocre procedural show.
More generally, it seems like a lot of sci-fi movies and tv shows resembles other non-sci-fi movies/shows, with advanced technology, spaceships, unexplained phenomena, aliens, etc ... being thrown into the mix. Sorta like using the "future" to tell stories about the present human condition.
When I was younger, I was mainly attracted to sci-fi from the futuristic technology and big guns. As I got older, I gradually came to the realization that a lot of sci-fi stuff wasn't much different than watching a cop show or an adventure movie.