The Big Bang Theory is absolute shit television.
I say this as someone who has watched since the pilot and has seen every episode. And there are many funny episodes, but it's your standard generic canned comedy. They are all already clones of each other. This one happens to be about geek guys who have trouble with women and like comics, but they are just sterile enough to be appealing to a wide demographic and thus it has success. It is no different from Lorre's other shows.