A is for A Deck....on Earth and later Federation starships that almost always means the main bridge.
B is for Beta Quadrant. Home of gaseous anomalies and an interstellar empire or two.
C is for Chapel. Nurse Chapel. Always a bridesmaid, never a bride.
D is for the Daystrom Institute.
E is for Excelsior.
F is for the Ferengi Tower of Commerce, the tallest building on Ferenginar and possibly the entire Ferengi Alliance.