If she is connected to anybody, I'd guess she's another chapter in the "Silence" saga, something to do with the forshadowed Fall of the Eleventh on the fields of Trenzilor (sp?).
There is a weird part of me that wants her to be related to the Cracks, some accident that fell through into different times when they rebooted the universe. I doubt that's what will happen, but it was a thought I had. So far the Eleventh Doctor's story has all been somewhat related.