A is for Astronauts on some kind of Star Trek.
B is for Brunt. Liquidator. FCA.
C is for Charlie X.'
D is for Defiant. At least three Federation starships bore this name.
E is for Excelsior. She's supposed to have transwarp drive.
F is for the Federation Council. It helped govern the UFP and was supposedly so awesome that, as of 2267, only one person had ever turned down a seat on it.
G is for Gamma II. Planetoid with an automatic communication and astrogation station.
H is for Heliopolis City, capital of the human colony on planet Alpha Eridani II and site of unsolved serial murders of women in 2156.
I is for Intertial damping. Techno-gobbledegook.
J is for Jim. His friends called him Jim.
K is for Klingon tea drinking rituals.
L is for Last of its Kind. The M-113 salt creature was one of these.
M is for the M-5. Once again; not entirely successful.
N is for Nog, the first Ferengi to ever attend Starfleet Academy.
O is for Organians. As high above us on the evolutionary scale as we are above the amoeba.
P is for Peace Treaty. The Federation had several with the Klingon Empire.
Q is for Q Continuum. Extradimensional domain of the Q.