Eh, it wouldn't be directly tied to Nemesis or anything. I just want something set 100 years after the TNG/DS9/VOY era. It'd essentially be a reboot as the world would have to be re-introduced to fans and casuals alike.
That would just be TNG redux. All TNG did was peal the labels off of TOS and put them on different bottles and then change the dates. Why use the knock off when you can use the originals?