^Spider-Man fans. I bought it, and don't regret doing so, but then I liked it *shrugs* and have been a Slott fan since he's been on the book.
Kaine won't be a factor in this IMO. He has a story of his own going on right now. Although it will be interesting to see if they have Superior encounter Scarlet Spider at some point since Kaine was responsible for killing Otto the first time I believe
Or at least snapped his neck, I don't know if that was retconned though when they brought Otto back.
I believe Peter will return well before "Amazing Spider-Man 2" comes out.