Re: Amazing Spiderman #700
Nothing I've read about the Marvel NOW! titles speaks to me as a jumping on point. Had Marvel gone for a full on New 52 style reboot then I'd agree, as they haven't, I don't.
Hell, most of the issues pick up directly after the closing stories of their predecessors.
"As a species we're fundamentally insane. Put more than two of us in a room, we pick sides and start dreaming up reasons to kill one another. Why do you think we invented politics and religion?" - Ollie, The Mist