Star Trek actors who have played John F. Kennedy:
- Cliff DeYoung (from DS9: "Vortex"): Robert Kennedy & His Times (1985)
- Andrew J. Robinson: Twilight Zone revival episode "Profile in Silver" (1986)
- Robert Pine (VGR/ENT guest and Chris Pine's father): TV movie Hoover vs. the Kennedys: The Second Civil War (1987)
- Steven Weber (from DS9: "The Siege"): The Kennedys of Massachusetts (1990)
- Stephen Collins: Miniseries A Woman Named Jackie (1991)
- Bruce Greenwood: Thirteen Days (2000)
- Steven Culp: Perception episode "Shadow" (2012)
I could also add noted Shatner impersonator Maurice LaMarche, who did a voice in a Trek video game and also voiced JFK on
Animaniacs.
It's worth noting that both
The West Wing's president and vice president, Martin Sheen and Tim Matheson, have played JFK. Also both cinematic Uncle Bens, Cliff Robertson and Sheen. While William Devane, who played JFK in
The Missiles of October, has also played the US President in
Stargate SG-1 and
The Dark Knight Rises.