Greg Cox wrote:

True. I guess it just depends on how flexible you wanna be when it comes to adhering to the letter of the original eps, as opposed to taking advantage of the unlimited makeup budget of the novels!
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Indeed. And with a ship that visits starbases every few months I don't see a reason why there can't be regular fluctuation among the crew.
The First Adventure had some Caitians among the crew, for example.
However, Memory Beta explains the Human-only ship that each of the four founding species was given a Constiution-class vessel, e.g. the
Intrepid for the Vulcans and the
Eagle for the Andorians.