Actually, there is strong precedent in Canon.
Voyager had no issues with Fluidic Space.
And the Enterprise in The Immunity Syndrome was essentially swimming inside a giant amoeba, certainly a liquid environment roughly analogous to water.
The functioning within a 1G environment is slightly more problematic, until you realize that a starship is travelling at warp velocities, and has survived close proximity to far more intense gravitationally induced stresses, to the point of surviving time travel.
Also in TOS they had an entire city floating on antigravity. They were impressed but not flabbergasted by it. Also in TNG they showed Galaxy class ships being build on Mars
Why didn't I think of Stratos?