I don't know about quality - my parents have a $50 webcam I bought them years ago, and I use my MacBook Pro built in camera. On their end, I look fantastic. On my end they look grainy and awful.
More concerning for me at the moment anyway is the repeated instances when Skype will (for some inexplicable reason) disconnect from video messaging after about 45-50 seconds. It's damn near impossible to have a conversation with anyone when it happens. At first I thought it was Charter Internet (because they're crooks and run a lousy service) but after idling away an hour on the phone with Charter we were able to determine that no, it wasn't their fault. I ran updates on Skype, and still seem to be having the problem, to the point that I just don't bother using it anymore.