StarTalk Radio is hosted by Neil deGrasse Tyson, director of the Hayden Planetarium in New York, author of several books on science, and host of the in-production remake of Cosmos
. Usually, Tyson and a comedian discuss science news and interview someone. I'm downloading this one now.
StarTalk Radio has done other Trek-themed shows before, interviewing both Whoopi Goldberg and Nichelle Nichols.