If you break things down, it's always a chemical issue in the brain.
Every human is different. Under the exact same level of stress, one makes it and feels fine, and the other one suffers from a burn out, for example. Of course because the body reacts physically differently to outside influence.
Of course you can go all-in with medication, and thus change your physical properties to solve that issue, but I really believe that it's better in the long run to solve the individual problem. In the case of the example above: reduce stress or find another form of stress that you can handle. It's not solved by "Try harder", mostly it's solved by "Try something different."
Basically, it's the alcohol thing. You have problems in life? No worries, let's have a drink and forget about it.
And it actually works, for some time at least.
But in the long run, it's better not to drink and solve the problems instead.