This is from Shatner's Rules, but it absolutely applied to me when I read the book last Christmas:
Think of all the things you have missed out on or avoided or didn't get to experience because you said "no." Think of all the adventures and good times and wonderful experiences you could have had, and will have all because you said "Yes."
Don't short-change yourself on the experience of life. SAY YES!
I've been trying to say yes to more opportunities because I tend to play it safe and it's time to try something different. I've had some great new food!
Also your first response was also acceptable. Like I said, it doesn't all have to be some epic advice. Use your turn signal is a very good recommendation!