How about the USS Stargazer with Narada's Romulan/Borg upgrades vs. one of those little Starfleet fighter ships from DS9 with a 2/3 powered up Gary Mitchell on board.
In a nebula.
Oh, and all the green buttons on the Stargazer aren't working. But the blue ones are okay. And the lighting's flickering Aliens-style, giving a few crewmen seizures.
But Gary has a bad case of carpal tunnel, which his godpowers can't heal.