C.E. Evans wrote:
There could always be a "Firefly-type" series that focuses on a civilian freighter that sometimes takes on jobs that aren't always on the up-and-up and may require them to fight their way out of situations that occasionally turn south on them. In that sense, Starfleet could be depicted as not the enemy, per se, but something the crew would like to avoid dealing with whenever possible.
At that point, using a civilian PMC or civilian equivalent of Starfleet would be preferable.
Running a freightor without weapons or very limited weapons wouldn't make as good of a base setup. Firefly worked well in that their usual solution was to run, hide, or evade attacks while airborne. While that is all well and good, if they were a PMC group with enough firepower, they could have interesting space battles.