It wouldn't be the first time a title has been re-used (as far as cities go, we've already had
Vega$,
Las Vegas and
Vegas, for example). And it's not like The Big Easy is a unique trademark, like
Star Trek or
The Munsters-- it's a well-known nickname for New Orleans, like The Big Apple for New York or The Hub for Boston. A bigger problem may be that it gives no indication that it's a genre show.