It wouldn't be the first time a title has been re-used (as far as cities go, we've already had Vega$
, Las Vegas
, for example). And it's not like The Big Easy is a unique trademark, like Star Trek
or The Munsters
-- it's a well-known nickname for New Orleans, like The Big Apple for New York or The Hub for Boston. A bigger problem may be that it gives no indication that it's a genre show.