At an equal technological level (which is the case), the larger ships wins, easily.
Meaning - Voyager gets fried against the Enterprise.
Why? No one on here has given any evidence as to why. The only thing people keep saying is that a larger ship has more power and more firepower. That has not been proven. These ships were built with exploration in mind, combat abilities are based on defense. The only time ships were used with true battle fashion were during the dominion war.
No one has given any proof that more power isn't just a misconception.