How about the original idea, "Wagon Train to the Stars"?
Lets take "Little House on the Prairie" and find a way to convert it to Star Trek. A family of pioneers settles on a planet, and while they try to build their home they encounter a bunch of science fiction horrors that they need to deal with.
It's Star Trek
. People are interested in space battles and strange new worlds
, not being stuck in one place. It's why Deep Space Nine
added the Defiant in season three. Because people weren't digging Trek being stationary.
Now a sci-fi Little House on the Prarie
isn't a bad idea in and of itself. But it would need to stand on its own outside the Trek universe.