Worf was one of the richest characters in all of Trek. He was the first Klingon in Starfleet and he has earned his way up the ranks and deserves to be captain. He served under two of the greatest captains of all time (Picard & Sisko - not to mention Riker) and the writers of such a story should have him grow and mature to the point where his style incorporates some traits of each. He should have some of the patience of Picard, the tenacity of Sisko and the unpredictability of Riker, as well as the warrior spirit and deep honor that Worf himself has always possessed. A post-Nemesis series should feature Worf commanding a ship with a crew filled with fresh characters.
This sounds on the money to me!