Well in First Contact they all just fired on the same spot and that did the trick, apparently.
Of course, First Contact is retarded, like all the TNG movies.
In that case, they had Picard, who was supposed to know where the vulnerable spot was somehow, because he was once assimilated.
I would have loved to have seen a long drawn out battle where they eventually take the Cube down without Picard knowing where to fire.
That would have had made the movie for me, just by itself.